A new preprint analysis from MIT researchers examines data from the CDC’s V-SAFE system—the smartphone app used to actively monitor health outcomes following Covid-19 vaccination.
Led by Retsef Levi and Nelson Lu, the analysis of responses from nearly 10 million people aged 16 and older found that 185,285 individuals (1.87%) reported health deterioration lasting three months or longer and attributed that decline to Covid vaccination.
Roughly half of this group—about 1% of all V-SAFE participants—described their outcomes as severe, including inability to work or perform daily activities, hospitalisation, or potentially disabling symptoms.
The V-SAFE survey reports, collected between December 2020 and mid-2023, remained largely inaccessible to independent researchers until FOIA litigation by Informed Consent Action Network forced their release.



