A new analysis has raised serious concerns about the safety of Covid-19 vaccination in early pregnancy.
Women who received an mRNA vaccine between 8 and 13 weeks gestation experienced a significantly higher rate of foetal loss—around 13 losses per 100 pregnancies—compared to an expected rate of just 9.
Published as a preprint by Guetzkow et al., the study analysed more than 220,000 pregnancies between 2016 and 2022 in Israel.
Among the authors are Retsef Levi, newly appointed to the CDC’s vaccine advisory panel, and Tracy Beth Høeg, now a senior advisor for clinical sciences at the FDA’s vaccine division.
The findings stand in sharp contrast to earlier studies, which found no increased risk—but most of those studies enrolled women who were vaccinated later in pregnancy, beyond the first trimester.